Detalhe da pesquisa
1.
Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage.
Proc Natl Acad Sci U S A
; 120(10): e2220828120, 2023 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848551
2.
Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.
PLoS Pathog
; 18(3): e1010375, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35294501
3.
Genome instability drives epistatic adaptation in the human pathogen Leishmania.
Proc Natl Acad Sci U S A
; 118(51)2021 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903666
4.
Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages.
J Cell Sci
; 134(5)2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32501279
5.
Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant.
J Eukaryot Microbiol
; 63(6): 823-833, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27216143
6.
Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology.
Proteomics
; 15(17): 2999-3019, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25959087
7.
Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.
Mol Microbiol
; 93(1): 146-66, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24823804
8.
The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status.
Mol Microbiol
; 93(1): 80-97, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24811325
9.
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
Antimicrob Agents Chemother
; 58(3): 1501-15, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366737
10.
Amphotericin B resistance correlates with increased fitness in vitro and in vivo in Leishmania (Mundinia) martiniquensis.
Front Microbiol
; 14: 1156061, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37089544
11.
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation.
Cell Microbiol
; 13(7): 978-91, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21501362
12.
Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage.
Eukaryot Cell
; 9(1): 22-30, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19801421
13.
Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses.
Proteomics
; 10(21): 3868-83, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20960452
14.
SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.
J Proteomics
; 213: 103617, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31846769
15.
Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines.
Parasit Vectors
; 13(1): 600, 2020 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256787
16.
Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models.
Front Cell Infect Microbiol
; 8: 325, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283743
17.
Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification.
mBio
; 9(6)2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401775
18.
New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence.
PLoS Negl Trop Dis
; 11(9): e0005924, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945751
19.
Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani.
Nat Ecol Evol
; 1(12): 1961-1969, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29109466
20.
Enhanced cloning efficiency of mouse bone marrow macrophage progenitors correlates with increased content of CSF-1 receptor of their progeny at low oxygen tension.
Microbes Infect
; 5(12): 1064-9, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14554247